To explore the possibility that reduction of cell growth by MEIS2 shRNA interference could correlate with increased apoptosis in these cells, or altered regulation of their responsiveness to chemotherapics, we performed Annexin-V assays on SKO-007(J3)/shMEIS2-Tet cells (where expression of MEIS2 was modulated by Doxy) in the presence of selected anti-MM drugs. Here, ANXA5 is linked to Miyoshi myopathy.