DU145 and PC3 cell lines retain cell surface markers such as CD49b/f, CD55 [24] which are reported to have potent role in cancer metastasis [25] [26] [27], through interaction of several pathways, whereas LNCaP cell line lacks these markers, which might be a possible reason for low invasion, migration, proliferation property of LNCaP. The gene discussed is CD55; the disease is cancer.