On the other hand, analysing the tumour-bearing animals subjected to leucine-rich diet, the Fig. 2 showed that the WL group exhibited similar of IRS-1 activity levels as those of the C group, which were slightly higher than those of the W group on the 21st day of the experiment (WL showed 1.9-times higher than W; P = 0.0628). Here, IRS1 is linked to neoplasm.