In a subpopulation analysis, an inverse relationship between the serum adiponectin level and urinary protein excretion rate in patients with type 2 diabetes with preserved GFR was attributed to the decrease in serum adiponectin associated with increased insulin resistance [15], whereas an increase in serum adiponectin levels has been established in patients with type 1 diabetes [16]. Here, ADIPOQ is linked to type 2 diabetes mellitus.