VEGFA and myocardial infarction: For example, combining VEGF165 and Ang1 improved the outcome in a diabetic rat model of myocardial infarction by reducing fibrosis and ventricular remodeling, along with increased angiogenesis.8 It has also been shown, in a rat dorsal skin flap model that the mechanism through which adenoviral‐mediated delivery of VEGF (through Ad.VEGF) increases tissue viability and blood flow is due to an increase in NO synthesis and release.9