To unveil the downstream genes involved in the tumor promoting role of CORO1C in human gastric cancer cells, several candidate genes (including EZH2, BCL‐2, cyclin D1, MDM2, vimentin and C‐myc) were selected according to the literature and our former work (they were oncogenes in gastric cancer and might be regulated by CORO1C), and we firstly examined the mRNA levels of these genes by RT‐qPCR after transfection with siCORO1C‐1 or siCORO1C‐2 in BGC‐823 cells. The gene discussed is MDM2; the disease is neoplasm.