SYTL5 and infection: Fig 6A summarizes the experimental plan and the eight treatments tested. Briefly, SLP5, surfactin, or DEPE was added to virus alone, cells alone, or to cells and virus together prior to infection, during virus adsorption, during virus invasion (1 h post infection at 37 °C), or during replication (1–12 hpi). Samples were harvested 12 hours after infection, and analyzed to measure cellular levels of viral protein (Fig 6B and 6C) and viral RNA (Fig 6D).