CXCR3 and neoplasm: Chemokines could inhibit angiogenesis, and CXCR3 was the main chemokin receptor in the process of inhibiting angiogenesis[12].In Mulle’s study, he pointed out CXCR4 only be found in cancer cells, they didn’t found in normal breast cells[13].Although there were some studies about the function of chemokines and their receptors for tumor metastasis, the sample size too small.