Long intergenic noncoding RNA 00511 (LINC00511) has been regarded as oncogene in several human cancers, such as tongue squamous cell carcinoma, pancreatic ductal adenocarcinoma and non‐small‐cell lung cancer.11, 12 Herein, we discover the oncogenic role of lncRNA LINC00511 in the glioma cellular progression, whose overexpression is motivated by the transcription factor specificity protein 1 (SP1). This evidence concerns the gene SP1 and glioma.