MTOR and early-onset autosomal dominant Alzheimer disease: For instance, the activation of mTOR‐dependent autophagy may delay neurodegenerative symptoms in fly and mouse models of Huntington's disease,35 and a mouse model of Alzheimer's disease.36 The present study found that with increased exposure time, the levels of p‐mTOR gradually decreased, which was negatively correlated with changes in p‐ULK1 and LC3II.