AKT1 and neoplasm: Existing studies have shown that EFEMP1 plays an important role in the progression of multiple tumors.6 In cervical cancer, high expression of EFEMP1 promoted the proliferation, invasion, and adhesion of tumor cells.7 In pancreatic cancer, EFEMP1 activated the mitogen‐activated protein kinase (MAPK) and protein Kinase B (PKB/AKT) pathways by binding to the EGF receptor to promote tumor proliferation.8 However, in some other tumors, EFEMP1 was considered to play a role in tumor suppression.