For example, in lung cancer, EFEMP1 inhibited tumor invasion by inhibiting MMP‐7 expression.9 In nasopharyngeal carcinoma, EFEMP1 inhibited cell migration and invasion by affecting the activity of AKT.10 In addition, EFEMP1 could be detected abnormally in the serum of tumor patients,11, 12 so it may serve as an important marker for clinical diagnosis of cancer. This evidence concerns the gene EFEMP1 and lung cancer.