In addition, a panel with BRCA1 mutation, BRCA2 mutation, and five serum markers (AFP, CA125, CA19‐9, CA242 and HE4) showed a good performance for identifying patients with lymph node metastasis (AUC = 0.843, Sensitivity = 0.600, Specificity = 0.902) (Table 4). Here, BRCA2 is linked to metastatic malignant neoplasm in the lymph nodes.