The levels of CA125, CA19‐9, CEA, Ferritin, NSE, and HE4 were significantly elevated (p = 2.82E‐24, 0.021, 0.029, 6.98E‐17, 1.92E‐06, and 1.63E‐07, respectively) and the level ofβ‐HCG was significantly reduced (p = 1.33E‐07) in ovarian cancer patients. This evidence concerns the gene WFDC2 and ovarian cancer.