In the combinations of different markers, a panel of eight markers (AFP, β‐HCG, CA125, CA15‐3, CEA, Ferritin, HGH, and NSE) showed the best performance in ovarian cancer detection (AUC = 0.873, Sensitivity = 0.727, Specificity = 0.826) (Table 4, Figure 1b). This evidence concerns the gene CEACAM5 and ovarian cancer.