A Pan‐Cancer analysis of 10 100 nonhypermutated cancers across 31 common cancer types from TCGA (Bailey et al., 2018; Gao et al., 2013) revealed that while CTNNB1 exon 3 mutations were present at 15–20% of liver, uterine, and adrenocortical carcinomas, mutations affecting CTNNB1 exon 3 are rare in other cancer types (< 3%; Fig. 1B). Here, CTNNB1 is linked to adrenal cortex carcinoma.