A panel of lung adenocarcinoma cell lines without targetable genetic alterations, including a KRAS wild‐type (H322), three KRAS mutant (A549, H358 and H460) and a KRAS wild‐type adenocarcinoma‐like mucoepidermoid carcinoma cell line (H292) 26, was selected to further investigate the relationship between EGFR and IFNγ pathway activation with PD‐L1 expression. Here, CD274 is linked to lung adenocarcinoma.