Altered expression of MT-CO2/COX2, and MT-ATP6 transcripts are significantly decreased in prostate tumor specimens [Gleason grade 5 (3 ± 2) to 8 (4 ± 4)] with a median of 7 (Abril et al., 2008), and the downregulation pattern of MT-ATP6 genes further supports our TRAMP expression dataset. Here, MT-ATP6 is linked to prostate neoplasm.