PTGS2 and cancer: Cancer metastasis signaling was linked with JAK kinase, Wnt family member 9A (WNT9A), IL6, and prostaglandin-endoperoxide synthase 2 (PTGS2); whereas interleukin 1 receptor associated kinase 4 (IRAK4), and histone h3 were associated with p38MAKP signaling pathway.