LRRC8E and lung carcinoma: KCNH2, REST, LRRC8E, PHF8, PCSK1, ANXA2, and MIR6730 have been also proved to be related to signaling pathway EGFR and lung cancer (Bonilla and Geha, 2006; de Castro et al., 2006; Kreisler et al., 2010; Wang et al., 2012; Demidyuk et al., 2013; Shen et al., 2014; D́ıaz-Rodŕıguez et al., 2018).