The selected significant features were FYN, KCNH2, REST, CDH12, LRRC8E, SCG2, PHF8, PCSK1, ANXA2, and MIR6730. FYN was an authentic Effector of oncogenic EGFR signaling, by limiting EGFR tumor cell motility (Lu et al., 2009). The gene discussed is SCG2; the disease is neoplasm.