TBXT and Decreased total monocyte count: Additonally, based on power calculations from our initial exploratory study in wild-type C57Bl/6J mice, it seems that while observations in sham-operated plg−/− mice were sufficiently powered, some observations in plg−/− mice undergoing MCAo were underpowered (including the lack of deterioration in neurological deficit and absence of monocytopenia following t-PA administration).