Showed antibacterial activity by production of bacteriocinReduced inflammation in epithelial cells of intestineReduced cholesterol level in serum. Produced an EPS known as kefiran.Reduced cholesterol, LDL, and triglyceride in male Sprague–Dawley (SD) ratsInduced apoptosis of Caco-2 and HT-29 cancer cells and decreased transforming growth factor (TNF-α and TNF-β) in HT-29Displayed anti-proliferative effect in different cancer cell lines. The gene discussed is TNF; the disease is cancer.