They also had significantly decreased percentage of CD8+CD25+ cells compared to patients in remission (3,92 ± 0,93 vs. 12 ± 0,75, p = 0,000163, ANOVA with post-hoc Tukey test) or depression (3,92 ± 0,93 vs. 8,68 ± 0,93, p = 0,005437, ANOVA with post-hoc Tukey test) as well as healthy people (3,92 ± 0,93 vs. 8,44 ± 0,63, p = 0,008647, ANOVA with post-hoc Tukey test, Fig. 3B). This evidence concerns the gene CD8A and depressive disorder.