CD4 and Behcet disease: BD patients in hypomania phase of the disease also were characterized by significantly lower percentage of CD3+CD4+ cells compared with healthy control (57,33 ± 2,64 vs. 75,38 ± 1,79, p = 0,000343, ANOVA test with post-hoc Tukey test) and patients in remission (57,33 ± 2,64 vs. 71,44 ± 2,15, p = 0,003788, ANOVA test with post-hoc Tukey test, Fig. 2A).