TNF and depressive symptom measurement: TNF-α concentration was significantly decreased in patients in remission compared to healthy people (1,85 ± 0,16 vs. 2,48 ± 0,13, p = 0,032135, ANOVA with post-hoc Tukey test) and patients in depression (1,85 ± 0,16 vs. 2,64 ± 0,22, p = 0,046543, ANOVA with post-hoc Tukey test Fig. 6B).