Although we did not detect the expression of CD4, CD56 or CD123 in murine tumors, which are commonly detected in BPDCN patients, these leukemic cells showed the murine pDC phenotype of CD11b−CD11cmid/+B220+Bst2+, accompanied by disseminative and transplantable capacities in secondary recipient mice. This evidence concerns the gene NCAM1 and CD4+/CD56+ hematodermic neoplasm.