Interestingly, ADM has been associated with blood lipid levels43 and with bipolar disorder46 and is a gene that promotes antimicrobial activity.47 Another three genes, in addition to obesity-related traits, also associate with psychotic disorders, such as schizophrenia (MYO1648 and ABCA149) or bipolar disorder (FPR350). This evidence concerns the gene ADM and obesity due to melanocortin 4 receptor deficiency.