IgM/IgG antibody detection (by enzyme-linked immunosorbent assay [ELISA] and lateral flow assay) is currently the method most commonly used to detect dengue diseases; however, it is inapplicable to the detection of DENVs in the early stages of infection and often produces false positives in cases where a patient has previously been infected with DENVs or other flaviviruses. The gene discussed is CD40LG; the disease is dengue disease.