Previous short term studies suggest that dutasteride but not finasteride might increase the risk of type 2 diabetes by impairing insulin sensitivity and increasing steatosis.8, 9, 13, 14, 19 Our pharmacoepidemiological analyses show that the incidence of type 2 diabetes was increased in patients with BPH receiving dutasteride compared with tamsulosin, but an increased risk was also seen in patients receiving finasteride. The gene discussed is INS; the disease is type 2 diabetes mellitus.