PAK1 and primary cutaneous T-cell non-Hodgkin lymphoma: Wang et al found that inhibition of PAK1 by IPA-3 suppresses cutaneous T cell lymphoma (CTCL) cell proliferation and promotes spontaneous apoptosis, interestingly, the inhibitory effects of IPA-3 on CTCL cells is similar to that of the lentiviral-based PAK1 gene knockdown vectors [10].