According to DIANA database several miRNAs from the «PCa» block, including miR-331 and miR-125, target genes, such as BRAF, GSK3B, E2F1, CDKN1A, CDKN1B, EGFR, AKT2, MAPK1, which interact with the ERBB pathway and are involved in the development of PCa. Here, E2F1 is linked to posterior cortical atrophy.