MYC and neoplasm: These results were supported by the bioinformatics analysis, which showed that Glut1 was correlated with HIF-1α, c-Myc, and EGFR expression in LUAD (Figure 7A), although another specific Glut1 inhibitor WZB117 did not show any effect on tumor growth in LUAD A549 and H1299 xenografts of mouse model (Goodwin et al., 2017).