By querying cBioportal TCGA GBM database [11, 12], we identified two mutations within the NF1-LRD domain that were also found in other cancer types such as cutaneous melanoma, colon carcinoma, and infiltrative breast carcinoma (cBioportal TCGA database, Tumor suppressor gene database, NCBI dbSNP, ClinVar, and Human Proteome Variation Database). The gene discussed is NF1; the disease is cancer.