CHD4 and cancer: The chromatin remodeling helicase CHD4, a component of the nucleosome remodeling and deacetylases (NuRD) complex, has been recently identified as an essential regulator of BC growth in murine and patient derived xenograft (PDX) BCs (D'Alesio et al., 2016) and correlates with poor prognosis in cancers (Nio et al., 2015; Xia et al., 2017).