For the simultaneous adjustment of expression by age and PCNA metagene (first A,P column), all of the cancers resulted in a significant KM logrank test for the best binarized PC; however, the empirical p-values for random selection of genes resulted in a significant KM test (second A,P column) for three cancers, namely, AML, bladder, and sarcoma. The gene discussed is PCNA; the disease is acute myeloid leukemia.