When we analyzed the expression levels of basal HBE1 mRNA in CRC cells (SW480, SW480-IR, SW620, SW620-IR, HT-29, HT-29-IR, RKO, and RKO-IR cells), we found that it was approximately 6-fold higher in radioresistant cells (SW480-IR, SW620-IR, HT-29-IR, and RKO-IR) than in respective radiosensitive cells (SW480, SW620, HT-29, and RKO cells) (Figure 2A, upper). Here, HBE1 is linked to colorectal carcinoma.