MCC950-treated IL-1β+/+ and untreated IL-1β-/- mice showed less weight loss and mortality, reduced IFN-γ and total protein levels, as well as leukocyte number in BAL, as compared to IL-1β+/+ mice without MCC950 treatment on day 5 post-infection (Fig 5B–5E). The gene discussed is IL1B; the disease is infection.