showed that DC‐SIGN binds Lactobacillus reuteri and Lactobacillus casei, but not Lactobacillus plantarum, driving the differentiation of Treg cells by stimulating monocyte‐derived DCs,98 suggesting that targeting of DC‐SIGN by certain probiotic bacteria may be beneficial to treat AD. This evidence concerns the gene CD209 and Alzheimer disease.