However, the majority of adult‐diagnosed asthma is Th2‐low and non‐atopic, and is often associated with high neutrophil concentrations and elevated Th17‐related responses.40, 41 Importantly, Th2‐high and Th2‐low forms of asthma exhibit distinct responses to corticosteroid treatment; Th2‐high asthmatics respond to this treatment, whereas Th2‐low patients are refractory.38 CLRs are thought to be involved in both forms of asthma (Fig. 2). The gene discussed is LARS1; the disease is asthma.