Other groups have demonstrated that anti-CD3-activated CD4 +T cells from ECs were resistant to HIV infection, independent of co-receptor usage (Chen et al., 2011; Sáez-Cirión et al., 2011; Paxton et al., 1996; Saha et al., 1998; Yu and Lichterfeld, 2011). The gene discussed is CD4; the disease is HIV infectious disease.