SRC and osteopetrosis: As Src knock-out mice do not exhibit CNS abnormalities, presumably because the knock-out is compensated by other SFKs, but have shortened lifespans and osteopetrosis-associated defects, the influence of Src activity on ethanol preference and consumption was investigated in mice harboring nonphosphorylatable (Ser75Ala) or phosphomimetic (Ser75Asp) Src mutants.