CD4 and Decreased total leukocyte count: We demonstrated that 18-day i.g. administration of WIE, UFP or WAE all accelerated the recovery of immunosuppressed mice from leukopenia and immunosuppression, supported by (1) the increased PWBC and spleen and thymus indexes, (2) normalized serum immunoglobulin level, (3) augmented splenocyte proliferation and NK cell activity, and (4) enhanced splenic CD3+ and CD4+ T lymphocyte subsets.