SH3PXD2B and Frank-Ter Haar syndrome: Several phenotypes of the Sh3pxd2b-KO C57Bl/6 mice recapitulate FTHS pathologies, including craniomaxillofacial malformations, growth retardation (manifested by reduced long bone size and body mass), glaucoma and kyphosis13; furthermore, like FTHS patients, the Tks4-deficient mice develop heart failure.