Interestingly, while the expression of ErbB2 in MPanc96 cells decreased dramatically in a relative short time exposure to VPA, it recovered to some extent upon prolonged treatment with VPA (Fig. 2), which may reflect the happening of a feedback upregulation of ErbB2 in MPanc96 cells being similar to a phenomenon reported in breast cancer cells previously [31, 32]. Here, ERBB2 is linked to breast carcinoma.