In the meantime, as a member of the IL-1 family of cytokines, ST2 (also known as T1, IL1RL1, or Fit1) measurements in blood samples could be a clinical prognostic biomarker useful in risk stratification of patients suffering from myocardial infarction, heart failure and dyspnea [34, 35]. This evidence concerns the gene IL1RL1 and heart failure.