CXCL8 and Familial prostate cancer: Prostate cancer cells pre-treated with EGCG (40 μg/mL, 24 h) and then transfected with CpG-ODN (1 μM, 6 or 24 h) showed a generalized inhibition of mRNAs for inflammatory cytokines such as IL-6, IL-8, CXCL-1, IP-10, CCL-5, TGF-β1, therefore experiencing a modulation of pathways that drive tumor growth [111].