Changes in eCB levels and also in the levels of its receptors and degrading enzymes, FAAH and MAGL, were observed both in blood and post-mortem brain samples of MS patients and in animal models of MS, such as the experimental autoimmune encephalomyelitis (EAE) model, in different stages of disease [379,383,388,389,390,391,392,393]. The gene discussed is FAAH; the disease is myeloid sarcoma.