Surprisingly, in Moreno-Jiménez et al. (2019) study, samples from patients with Alzheimer’s disease (AD) also have immature progenitor cells, i.e., DCX positive cells, although the number and maturation of these cells progressively declined as AD advanced, again reinforcing the idea that tissue handling is essential for the preservation and detection of neurogenic markers [115]. This evidence concerns the gene DCX and Alzheimer disease.