FOXP3 and Alzheimer disease: Similarly, L. plantarum IS-10506 attenuated the levels of specific inflammation markers, such as IL-4, IL-17, and interferon-γ (IFN-γ), and increased the expression of immunomodulatory factors Forkhead box P3 (Foxp3+) and IL-10 in BALB/c mice, as well as in pediatric AD patients that had orally received this probiotic strain.