Since we had observed enhanced chemokine expression in the IFITKO hearts soon after infection (S7 Fig), we analyzed infiltration of macrophages by staining heart vibratome sections with an antibody against Iba-1 (Ionized calcium-binding adaptor molecule 1, also known as Aif-1), a protein that is predominantly expressed on cells of the macrophage lineage [23]. The gene discussed is AIF1; the disease is infection.