Gene signatures of subpopulations A, B, and C, brainstem (subpopulations A, C), olfactory bulb (subpopulations A, B, C, E), cortex (subpopulations B, C), amygdala, striatum, hippocampus, reactive astrocytes (RAs), and scar-forming astrocytes (SAs) in SCI had significant positive correlations with GBM samples with a combined set of genomic features that included amplification of the EGFR gene and deletions of the CDKN2A and MTAP genes. The gene discussed is MTAP; the disease is glioblastoma.