FOXRED1 and pulmonary arterial hypertension: With interest we read the article by Apatean et al. about a female neonate presenting with intrauterine growth retardation, lactic acidosis, periventricular cysts, cerebral demyelination, and pulmonary hypertension(pH), being attributed to the compound heterozygous variants c.612_615dupAGTG and c.847G>A in FOXRED1 [1].