CXCL8 and Sepsis: miR-30d-5p down-regulation and its inverse correlation between the levels of pro-inflammatory cytokines (IL-1, IL-6, IL-8 and others) were noted in severe sepsis (Caserta et al., 2016) suggesting that its up-regulation associated with music-performance might confer antagonistic effects consistent with findings from the RNA expression study (Kanduri et al., 2015a).