MS-275 similarly increased the protein levels of STAT1 and phosphorylated STAT1 in MM.1S and KMS11 cells in the presence of IFN-γ (Supplementary Figure 2B), and the HDAC6 inhibitor ACY-1215 also upregulated PD-L1 expression on these MM cells (Supplementary Figure 2C). This evidence concerns the gene IFNG and Miyoshi myopathy.