In the stratified analysis, for individuals with no minor allele at rs74826777 (RGL1 gene), rs17835244 (RAD51B) does not impact lung cancer risk (p value = 0.51); but for individuals with at least one copy of minor alleles at rs74826777, rs17835244 displays a protective effect for lung cancer with OR 0.46 and p value of 1.22x10-8 (Figure 3A). This evidence concerns the gene RGL1 and lung cancer.