Seven of these overlapped GWAS genes associated with T2D alone (AP3S2, GPSM1, MAEA, TLE4, TMEM163, SSR1, and UBE2Z), three with T2D associated traits alone (IGF1R for fasting plasma glucose, ABO for disposition index and UHRF1BP1 for fasting plasma insulin), and one for both T2D and fasting glucose levels (ADCY5). This evidence concerns the gene TMEM163 and type 2 diabetes mellitus.