To further demonstrate that G0S2 regulates glioma radioresistance through 53BP1, we knocked down 53BP1 using shRNAs in U87/G0S2 and LN229/G0S2 cells and determined γ-H2AX expression and γ-H2AX foci formation in response to IR. This evidence concerns the gene TP53BP1 and glioma.