The AUC for early stage, resectable pancreatic cancers was 0.91 (95% CI 0.85–0.95) for ADAMTS1, AUC 0.78 (95% CI 0.70–0.85) for BNC1 alone, while the AUC of the two-gene combination was 0.95 (95% CI 0.90–0.98). This evidence concerns the gene ADAMTS1 and familial pancreatic carcinoma.